Tangle Creek is a medium priority water. The creek has perennial stretches and seemingly robust populations of longfin dace and lowland leopard frogs and serves as a donor creek for longfin dace translocation to other sites. Management needs include survey, inventory, and monitoring, specifically to monitor native population status and remove non-native species. Although no desert sucker records exist for Tangle Creek, portions of this creek may be suitable for this species.
